Mad'House Cover: Dutch Eurotrash group Mad'House's claim to fame is their blasphemous take on "Like a Prayer" from 2002. The glorified Madonna cover band's version is stripped of the original's nuance and soul, a tacky, mechanical shell of a dance track. Regrettably, this is the version you're most likely to hear on Top 40 radio today. (Only slightly less heretical, the cast of Glee's rendition of the song peaked at #27 in 2010.)
MTV On Stage & On the Record: Then notorious for forsaking her older material, Madonna dusted off "Like a Prayer" in 2003 during the promotion of her album American Life. Thirteen years after her last live performance of the song, even Madonna's comparatively reedier voice and noticeably more limited range couldn't diminish its enduring magic.
Sticky & Sweet Tour: After performing crowd-pleasing but relatively anemic versions of "Like a Prayer" during her Re-Invention Tour in 2004 and Live 8 in 2005, Madonna reinvented the song for her Sticky & Sweet Tour in 2008, using elements of Mack's "Feels Like Home" for an amped-up techno mash-up.
The Super Bowl: Madonna closed her record-breaking Super Bowl XLVI halftime show in 2012 with "Like a Prayer," and though she wasn't singing live, it was the closest she's ever gotten to her ecstatic Blond Ambition performances. (For those lamenting the lip-synching, she would go on to reprise this version of the song, completely live, during her MDNA Tour later that year.) And if there were any doubt, a stadium of nearly 70,000 football fans waving flashlights and singing along is a testament to the song's transcendent, all-encompassing appeal. The performance's final message of "World Peace" seemed attainable, if only for a brief moment.